Concerted regulation of npc2 ... - Login to TUT/Intranet Manuals & Documents
Favorable membrane binding orientations of NPC2 with a low interconversion barrier. The first binding mode (Prone) places the cholesterol binding pocket in direct contact with the mem-brane and is characterized by membrane insertion of a loop (V59-M60-G61-I62-P63-V64-P65).
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